Table 1.
Affinity resins
Resin | Binding capacity | Strong binding to animal species (IgG) | Medium binding (IgG) |
---|---|---|---|
Protein G Sepharose 4 Fast Flow | 17–23 mg IgG/mL | Human (all subtypes), NHP, rabbit, cow, horse | Rat, mouse, guinea pig, goat, sheep |
rProtein A sepherose Fast Flow | 35 mg IgG/mL | Human (not IgG3 subtype), NHP, rabbit, guinea pig, mouse (IgG2) | Cow, dog, horse, mouse (IgG1 and IgG3) |
CaptureSelect IgG-Fc multispecies | 25 mg IgG/mL | Human (all subtypes), NHP, mouse, rabbit, donkey, horse, hamster, sheep, guinea pig | Cow, goat, pig, cat, rat |