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. 2023 Jul 15;33:376–390. doi: 10.1016/j.omtn.2023.07.010

Figure 4.

Figure 4

PANoptosis signature predicts the prognosis and immunotherapy response of patients with PRAD

(A) The differences in survival probability between the high- and low-signature score groups. (B) Prognostic prediction of PANoptosis signature scores in the TCGA cohort. (C) Survival outcomes in melanoma patients treated with anti-PD-1 monotherapy (PMID30753825). (D and E) Correlation between the PANoptosis signature score and clinical response to cancer immunotherapy in patients with melanoma treated with anti-PD-1 monotherapy (PMID30753825). (F) Survival outcomes in melanoma patients treated with combined anti-PD-1 and anti-CTLA-4 therapy. (G and H) Correlation between the PANoptosis signature score and clinical response to cancer immunotherapy in patients treated with combined anti-PD-1 and anti-CTLA-4 therapy. CR, complete response; PR, partial response; PD, progressed disease; SD, stable disease. CR/PR, patient with CR or PR; SD/PD, patient with SD or PD.