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. 2023 Apr 17;29(9):2690–2704. doi: 10.1111/cns.14213

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© 2023 The Authors. CNS Neuroscience & Therapeutics published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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PTX3 upregulation promoted the malignant phenotype of t‐DCs. (A, B) The transfection efficiency was verified by qRT‐PCR and western blot. (C) CCK8 assay on t‐DCs with PTX3 upregulation. (D) Clone formation assay on t‐DCs with PTX3 upregulation. (E, F) Transwell and wound healing assay of t‐DCs with PTX3 upregulation. (G) Tumorigenicity assay performed in nude mice by subcutaneous inoculation of t‐DCs with PTX3 upregulation. Data are expressed as mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001.