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. 2023 Apr 17;29(9):2690–2704. doi: 10.1111/cns.14213

FIGURE 6.

FIGURE 6

PTX3 is involved in ZNF148‐mediated malignant phenotypes. (A) Levels of PTX3 in t‐DCs transfected with si‐NC, si‐ZNF148, or si‐ZNF148 with PTX3‐overexpression plasmids by western blot. (B, C) CCK8 and clone formation assay of t‐DCs transfected with si‐NC, si‐ZNF148, or si‐ZNF148 with PTX3‐overexpression plasmids. (D, E) Transwell and wound healing assay of t‐DCs transfected with si‐NC, si‐ZNF148, or si‐ZNF148 with PTX3‐overexpression plasmids. (F) Tumorigenicity assay performed in nude mice by subcutaneous inoculation of t‐DCs with sh‐NC, sh‐ZNF148, or sh‐ZNF148 with PTX3‐overexpression. (G) Flow cytometry on cell apoptosis of t‐DCs transfected with si‐NC, si‐ZNF148, or si‐ZNF148 with PTX3‐overexpression plasmids. (H) Cell cycle assay of t‐DCs transfected with si‐NC, si‐ZNF148, or si‐ZNF148 with PTX3‐overexpression plasmids. Data are expressed as mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001.