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. 2023 Aug 2;7(1):e001334. doi: 10.1136/bmjpo-2021-001334

Table 3.

Factors associated with adequate levels of protective antitetanus antibodies among newborns

Variable Crude PR Adjusted PR 95% CI P value
Maternal TT antibodies (IU/mL)
 <0.1 1 1
 ≥0.1 3.3 (1.6–7.0) 3.1 1.5 to 6.4 0.002
Gestation at first ANC visit
 ≤12 weeks 1 1
 >12 weeks 1.3 (1.0–1.6) 1.2 1.0 to 1.5 0.030
Gestation at last TD dose
 <28 weeks 1 1
 ≥28 weeks 1.3 (1.1–1.5) 1.1 1.0 to 1.3 0.034
TT/TD doses before current pregnancy
 <5 doses 1 1
 ≥5 doses 0.94 (0.84–1.1) 0.94 0.85 to 1.0 0.244
TT/TD doses during current pregnancy
 0–1 1 1
 2 1.2 (1.1–1.3) 1.1 1.0 to 1.2 0.025
 3–4 1.3 (1.2–1.4) 1.1 1.0 to 1.2 0.004
Maternal age (years)
 ≤20 1 1
 21–30 1.1 (0.97–1.3) 1.1 0.95 to 1.2 0.259
 >30 1.0 (0.88–1.2) 1.0 0.86 to 1.2 0.865
Birth weight (kg)
 ≥2.5 1 1
 <2.5 0.80 (0.66–0.97) 0.86 0.74 to 1.0 0.059
HIV
 No 1 1
 Yes 0.94 (0.80–1.1) 1.0 0.92 to 1.17 0.555
High blood pressure (>140/90 mm Hg)
 No 1 1
 Yes 1.0 (0.85–1.2) 1.0 0.92 to 1.2 0.608
Febrile (>37.5°C)
 No 1 1
 Yes 1.0 (0.91–1.1) 1.0 0.91 to 1.1 0.936

ANC, antenatal care; PR, prevalence ratio; TD, tetanus diphtheria; TT, tetanus toxoid.