Table 1.
RA patient characteristics
| General characteristics | Overall RA population (n=97) |
Female RA (n=76) |
Male RA (n=21) |
P value |
| Age (years) | 59.4±13.2 | 57.4±13.0 | 66.4±12.2 | <0.01 |
| RA duration (years) | 13.1±11.0 | 13.4±10.9 | 12.1±11.6 | NS |
| ACPA positive | 78 (83.0) | 57 (75.0) | 21 (100) | <0.05 |
| RF positive | 76 (84.4) | 58 (76.3) | 18 (85.7) | NS |
| Erosive RA | 80 (84.2) | 61 (80.3) | 19 (90.5) | NS |
| Tobacco users | ||||
| Never a smoker | 60 (61.9) | 56 (73.7) | 4 (19.0) | <0.0001 |
| Current smoker | 14 (14.4) | 9 (11.8) | 5 (23.8) | NS |
| Former smoker | 23 (23.7) | 11 (14.5) | 12 (57.1) | <0.001 |
| Occupation | ||||
| Never worked or student | 6 (6.4) | 6 (7.9) | 0 (0) | NS |
| Active worker | 29 (30.8) | 23 (30.3) | 6 (28.6) | NS |
| Non-active worker (retired or unemployed) | 59 (62.8) | 48 (63.2) | 11 (52.4) | NS |
| RA treatments | ||||
| MTX | 53 (54.6) | 42 (55.3) | 11 (52.5) | NS |
| bDMARDs | 54 (55.7) | 44 (57.9) | 10 (47.6) | NS |
| Never bDMARDs user | 30 (30.9) | 23 (30.3) | 7 (33.3) | NS |
| bDMARD 1st line | 37 (38.1) | 31 (40.8) | 6 (28.6) | NS |
| bDMARD 2nd line | 18 (18.6) | 13 (17.1) | 5 (23.8) | NS |
| bDMARD 3rd line | 6 (6.2) | 5 (6.6) | 1 (4.8) | NS |
| bDMARD >3rd line | 6 (6.2) | 4 (5.3) | 2 (9.5) | NS |
| Chest HRCT scan | 62 (63.9) | 50 (65.8) | 12 (57.1) | NS |
| Normal HRCT chest scan | 12 (19.3) | 12 (24.5) | 0 (0) | NS |
| ILD | 11 (18.0) | 7 (14.3) | 4 (16.7) | NS |
| Emphysema | 12 (19.7) | 5 (10.2) | 7 (58.3) | <0.001 |
| Mediastinal lymph nodes | 17 (27.4) | 12 (24.5) | 5 (41.7) | NS |
| Pulmonary nodules* | 18 (29.0) | 13 (26.5) | 5 (41.7) | NS |
Data are expressed as absolute number and percentage (%) or mean (SD).
*Nodules or micronodules.
ACPA, anticitrullinated protein antibody; bDMARD, biologic disease-modifying antirheumatic drug; HRCT, high-resolution CT; ILD, interstitial lung disease; MTX, methotrexate; NS, not significant; RA, rheumatoid arthritis; RF, rheumatoid factor.