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. 2023 Jul 21;13:1222716. doi: 10.3389/fonc.2023.1222716

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Copyright © 2023 Dong, Zhang, Jiang, Wei, Wang, Yang, Yan, Chen, Zheng, Shao and Xiong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Changes in ctDNA abundance after EGFR-TKI treatment (dotted line) and chemotherapy (solid line) in 11 postoperative MRD-positive adenocarcinoma patients; X-axis represents follow-up time, Y-axis represents ctDNA abundance; (B) in vivo tumour ctDNA abundance in 4 patients with MRD-positive squamous cell carcinoma treated with chemotherapy + ICIs; X-axis represents follow-up time, Y-axis represents ctDNA abundance.