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. 2023 Aug 4;2023(8):CD006006. doi: 10.1002/14651858.CD006006.pub3

Comparison 2. Prostaglandins compared with placebo/standard care: subgroup analyses.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 All‐cause mortality 11   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.1.1 Prostaglandins versus placebo 7 534 Risk Ratio (M‐H, Random, 95% CI) 0.92 [0.61, 1.40]
2.1.2 Prostaglandins versus standard care 4 237 Risk Ratio (M‐H, Random, 95% CI) 0.74 [0.29, 1.87]
2.2 Liver retransplantation 6   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.2.1 Prostaglandins versus placebo 3 289 Risk Ratio (M‐H, Random, 95% CI) 1.13 [0.49, 2.62]
2.2.2 Prostaglandins versus standard care 3 179 Risk Ratio (M‐H, Random, 95% CI) 0.71 [0.20, 2.46]
2.3 Primary non‐function 7   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.3.1 Prostaglandins versus placebo 4 407 Risk Ratio (M‐H, Random, 95% CI) 0.70 [0.29, 1.70]
2.3.2 Prostaglandins versus standard care 3 217 Risk Ratio (M‐H, Random, 95% CI) 0.19 [0.02, 1.64]
2.4 Acute kidney failure requiring dialysis 5   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.4.1 Prostaglandins versus placebo 4 398 Risk Ratio (M‐H, Random, 95% CI) 0.43 [0.23, 0.81]
2.4.2 Prostaglandins versus standard care 1 79 Risk Ratio (M‐H, Random, 95% CI) 0.38 [0.11, 1.29]