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. 2023 Jul 21;29(27):4289–4316. doi: 10.3748/wjg.v29.i27.4289

Table 4.

ECG changes, PQ interval, QTc interval, msec, heart frequency, beats/min, in rats at 15 min and 60 min following stomach perforation

Application of the 1 mL/rat through the perforated defect in the injured stomach at 5 min following perforation ECG changes in rats at 15 min and 60 min following stomach perforation
15 min
60 min
PQ interval, msec mean ± SD
Control 64 ± 5 67 ± 6
BPC 157 10 μg/kg 50 ± 5a 50 ± 5a
BPC 157 10 ng/kg 50 ± 5a 50 ± 5a
QTc interval, msec, mean ± SD
Control 312 ± 10 347 ± 10
BPC 157 10 μg/kg 180 ± 10a 188 ± 10a
BPC 157 10 ng/kg 185 ± 10a 183 ± 10a
Heart frequency, beats/min, mean ± SD
Control 530 ± 30 550 ± 30
BPC 157 10 μg/kg 375 ± 10 a 360 ± 10a
BPC 157 10 ng/kg 385 ± 10 a 365 ± 10a
a

P < 0.05, at least vs control.

ECG changes, PQ interval, QTc interval, msec, heart frequency, beats/min, in rats at 15 min and 60 min following stomach perforation. Saline (5 mL/kg, control) or BPC 157 (10 μg/kg and 10 ng/kg) were given at 5 min thereafter.