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. 2023 Aug 4;21:253. doi: 10.1186/s12951-023-02006-x

Fig. 7.

Fig. 7

Gene expression of CAFs in the tumor microenvironment in tumor-bearing mice. a mRNA expression of CAF-related genes was decreased in the treatment group. b Reduced gene expression of chemokines. c Decreased gene expression of the TGFβ family in the treatment groups. Grey, PBS; pink, intravenous (IV) administration; blue, intracranial (IC) administration. de After treatment with GENs, α-SMA immunohistochemical staining in the brain tissue was determined (brown) (*, P < 0.05; **, P < 0.01; ***, P < 0.001)