Fig. 2.

Differences in thalamic connectivity patterns between sensory and association cortical parcels. (A) Resting-state functional connectivity networks identified by Ji et al. (45). The 360 cortical parcels were assigned to twelve functional networks, including eight association and four sensory networks. (B) $E{D}_{pc1}$ loadings for each network, representing the average $E{D}_{pc1}$ loading within the network for each subject. Barplots show the mean and standard error. (C) Sensory networks exhibited significantly higher $E{D}_{pc1}$ loadings compared to association networks (two-sided Wilcoxon signed-rank test; *** p < 0.001). (D) Cortical myelin map calculated by averaging T1w/T2w values across subjects. (E) Cortical principal functional gradient loading ($RSF{C}_{pc1}$) map derived from PCA on cortico-cortical resting-state functional connectivity data. Sensory cortical parcels displayed higher T1w/T2w values and $RSF{C}_{pc1}$ loadings compared to association cortical parcels. (F,G) Correlations between $E{D}_{pc1}$ loadings and T1w/T2w values, as well as $RSF{C}_{pc1}$ loadings, across the cortex. (H,I) On average, a moderate relationship was observed between $E{D}_{pc1}$ loadings and T1w/T2w values, as well as $RSF{C}_{pc1}$ loadings, across subjects.