Fig. 4.

Relationship between the extent of cortical connections within the thalamus and overlap with thalamic subpopulations and intrinsic timescale across cortex. (A) Thalamic gradient reflecting the relative mRNA expression of Parvalbumin (PVALB) and Calbindin (CALB1)-expressing thalamic subpopulations ($C{P}_t$) (62). Warmer colors indicate higher CALB1 expression relative to PVALB. (B) $C{P}_t$ and $P\mathit{L-A}{M}_t$ values strongly correlated with one another. (C) Cortical map showing the overlap between anatomical connectivity and $C{P}_t$ values ($C{P}_c$). Warmer colors denote preferential coupling with CALB1-expressing thalamic populations. (D) $E{D}_{pc1}$ loadings and $C{P}_c$ values significantly correlated with one another. (E) Cortical map of z-transformed intrinsic timescale $\left(\tau \right)$, calculated from group-averaged resting-state data (63). (F) $E{D}_{pc1}$ loadings and z-transformed $\tau$ values exhibited a trending correspondence when accounting for spatial-autocorrelation.