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. 2015 Dec;21(12):10.18553/jmcp.2015.21.12.1124. doi: 10.18553/jmcp.2015.21.12.1124

TABLE 2.

Logistic Regression Analysis Comparing Likelihood of Having 6 or More Prescription Claims for SABA Among Adherent Versus Nonadherent Patients (N = 32,172)a

  Odds Ratio 95% CI Wald X2 P Valueb
Adherence to Controller Therapyc
  Controller adherence (PDC ≥ 50%) 1.967 1.826 2.120 313.9342 < 0.0001
Covariates
Treatmentc
  LTRA 0.697 0.641 0.757 72.0152 < 0.0001
  ICS/LABA fixed dose dual therapy 1.070 0.975 1.174 2.0141 0.1558
  ICS+LTRA concurrent dual therapy 1.662 1.492 1.851 85.0794 < 0.0001
  ICS/LABA fixed dose + LTRA 1.962 1.779 2.165 181.2997 < 0.0001
Age groupc
  5-11 0.832 0.748 0.925 11.5388 0.0007
  12-18 0.881 0.788 0.985 4.9318 0.0264
  19-40 1.114 0.975 1.273 2.5148 0.1128
  Female 0.844 0.795 0.896 30.9044 < 0.0001
Race/ethnicityc
  African American 1.322 1.214 1.440 41.1367 < 0.0001
  Hispanic 0.881 0.788 0.985 15.6113 < 0.0001
  Otherd 1.114 0.975 1.273 0.0176 0.8943
  Total number of nonstudy medications 1.052 1.043 1.061 132.3529 < 0.0001

a Model chi-square = 1427.56, df = 10, P < 0.0001.

b Significant at P < 0.05.

c Reference categories: nonadherence (PDC < 50%), ICS, 41-63 years, Caucasian.

d American Indian, Asian, unknown.

CI = confidence interval; ICS = inhaled corticosteroids; LTRA = leukotriene receptor agonists; PDC = proportion of days covered; SABA = short-acting beta2-agonists.