Table 5:
Metrics and definitions for evaluation against SIRVs.
| Reference SIRV (rSIRV) | Ground truth SIRV model |
|---|---|
| SIRV_transcripts | Transcripts mapping to a SIRV chromosome |
| SIRV_RM | SIRV_transcripts associated to at True Positive |
| True Positive detections (TP) | rSIRVs identified as RM |
| Partial True Positive detections (PTP) | rSIRVs identified as ISM or FSM_non_RM |
| False Negative (FN) | rSIRVs without FSM or ISM |
| False Positive (FP) | NIC + NNC + antisense + fusion SIRV_transcripts |
| Sensitivity | TP/rSIRVs |
| Precision | RM/SIRV_transcripts |
| Non_redundant Precision | TP/SIRV_transcripts |
| Positive Detection Rate | unique(TP+PTP)/rSIRVs |
| False Discovery Rate | (SIRV_transcripts - SIRV_RM)/SIRV_transcripts |
| False Detection Rate | FP/SIRV_transcripts |
| Redundancy | (FSM + ISM)/unique(TP+PTP) |