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[Preprint]. 2023 Jul 28:2023.07.25.23293180. [Version 1] doi: 10.1101/2023.07.25.23293180

Table 3.

Association of polygenic score of 204 known CAD variants and incident CVD in people with T2D.

Ancestry HR 95% CI Het P P
European/European American 1.18 1.14 – 1.21 0.010 <1.0×10−16
African American 1.10 1.05 – 1.15 0.255 8.3×10−5
Hispanic/Latinx 1.10 1.03 – 1.18 0.474 0.0031
East Asian 0.99 0.88 – 1.13 0.586 0.982
Overall 1.14 1.12 – 1.16 0.002 <1.0×10−16

Polygenic score of 204 CAD variants discovered from the general population was associated with increased risk of incident CVD in people with T2D. CI, confidence interval; Het P, significance of heterogeneity; HR, hazard ratio.