Fig. 7. The Dsup HMGN-like domain and downstream C-terminal sequences redundantly contribute to survival during oxidative damage.

(a). Schematic of Dsup alleles (all containing N-terminal 6xHIS and C-terminal FLAG tags (not depicted; see also Fig. 2a), including Dsup HMGN ΔC+NLS (Δ374–445 followed by an exogenous NLS (PKKKRKVPKKKRKV)). (b). Western blotting of expression levels (see also Fig. 2c). (c). Sensitivity to oxidative DNA damage (H₂O₂ ; see also Fig. 1b).