TABLE 2.
Experimental infection of pigs with SVDVsa
| Virus | Dose (TCID50) | No. of pigsb | Mean lesion scorec (range) | Seroconversiond
|
|
|---|---|---|---|---|---|
| No. seropositive/no. tested | Mean titer (range)e | ||||
| vSVLSJ1 | 108.0 | 5 (TK21–25) | 12.4 (4–29) | 5/5 | 2.59 (2.11–3.16) |
| vSVLS00 | 108.3 | 5 (TK26–30) | 0 | 2/5 | 0.75 (<0.6–0.75) |
| vSVLS5’J1 | 108.0 | 5 (TC91–95) | 0.4 (0–2) | 1/5 | 1.04 (0.72–1.44) |
| vSVLS5’00 | 108.0 | 5 (TC86–90) | 30.8 (18–45) | 5/5 | 2.28 (2.17–2.53) |
| vSVLSP1J1 | 108.3 | 5 (TK65–69) | 11.6 (4–24) | 5/5 | 2.23 (2.11–2.41) |
| vSVLSP100 | 107.5 | 5 (TK70–74) | 0 | 4/5 | 1.14 (1.05–1.51) |
| vSVLS1CD2AJ1 | 108.5 | 5 (TK75–79) | 19.4 (5–27) | 5/5 | 2.59 (2.41–2.71) |
| vSVLS1CD2A00 | 108.2 | 5 (TK80–84) | 0 | 3/5 | 0.99 (0.90–1.05) |
| vSVLS104/201MJ1 | 108.3 | 5 (TK31–35) | 8.4 (7–12) | 5/5 | 1.87 (1.51–2.11) |
| vSVLS104/201M00 | 107.9 | 5 (TK36–40) | 0 | 4/5 | 2.11 (<0.6–2.26) |
a
All animals were inoculated intradermally with a 1-ml injection into the bulb of the heel. Each animal weighed 20 kg.
b
Five animals per group. The animal designations are in parentheses.
c
Scored at 10 days postinfection.
d
Seroconversion is defined as a ≥4-fold rise in the titer at any stage after infection.
e
Mean titer at 14 days postinfection (reciprocal log10).