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Stability studies.
| Parameter | Nanoformulation without lyoprotectant (NF) | Nanoformulation with mannitol (NFM) | ||||
|---|---|---|---|---|---|---|
| 0th day | 90th day | 180th day | 0th day | 90th day | 180th day | |
| Particle size (nm) | 261 ± 3 | 263 ± 8 | 259 ± 3 | 194 ± 4 | 195 ± 3 | 195 ± 7 |
| PDI | 0.78 | 0.76 | 0.76 | 0.48 | 0.47 | 0.48 |
| Zeta Potential (mV) | +38.13 ± 0.3 | +37.43 ± 0.5 | +37.90 ± 0.6 | +36.13 ± 0.8 | +36.98 ± 1.1 | +35.18 ± 0.5 |
