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. 2023 Apr 17;12(5):e230006. doi: 10.57264/cer-2023-0006

Table 3. . Univariate analysis and multivariate analysis of factors associated with progression-free survival in patients after progression-free survival.

  mPFS, month (95% CI) Univariate analysis Multivariate analysis
    HR (95%CI) p-value HR (95%CI) p-value
Sex
  Male
  Female

10.8(9.3–12.3)
8.8(6.2–11.5)

0.987 (0.684–1.424)

0.945

1.142 (0.673–1.937)

0.622
Age
  <65 years
  ≥65 years

11.0 (9.3–12.7)
9.5 (6.6–12.3)

1.003 (0.710–1.418)

0.987

0.984 (0.691–1.401)

0.929
ECOG
  0
  1

10.6 (9.1–12.1)
8.9 (3.1–14.7)

1.085 (0.752–1.565)

0.664

0.954 (0.649–1.403)

0.812
Smoking status
  Never
  Current/former

9.2 (7.1–11.3)
11.1 (9.1–13.1)

0.932 (0.663–1.309)

0.684

1.113 (0.685–1.808)

0.664
Brain metastases
  No
  Yes

11.0 (9.2–12.8)
7.3 (5.0–9.6)

2.063 (1.289–3.301)

0.003

2.448 (1.463–4.096)

0.001
Liver metastases
  No
  Yes

11.1 (9.5–12.7)
6.8 (5.9–7.7)

1.821 (1.091–3.038)

0.022

1.963 (1.155–3.336)

0.013
Bone metastases
  No
  Yes

11.4 (9.3–13.6)
7.1 (4.8–9.4)

1.542 (1.096–2.169)

0.013

1.688 (1.137–2.507)

0.009
Stage
  IIIB/IIIC
  IV

11.1 (7.3–15.0)
9.7 (7.9–11.4)

1.027 (0.591–1.785)

0.926

0.695 (0.380–1.273)

0.239
Treatment regimens
  BC
  IC

8.2 (6.3–10.1)
13.5 (10.9–16.1)

0.637 (0.456–0.889)

0.008

0.674 (0.479–0.947)

0.023

HR: Hazard Ratio; PFS: Progression-free survival.