Table 2.
ECG parameters.
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ALL | TRAINING COHORT | TEMPORAL VALIDATION COHORT | |||||||
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HOCM N = 132 | HNCM N = 102 | P | HOCM N = 102 | HNCM N = 70 | P | HOCM N = 30 | HNCM N = 32 | P | |
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P, ms | 106 [100, 114] | 100 [92, 107] | <0.001 | 104 [100, 110] | 100 [90, 106] | <0.001 | 112 [104, 122] | 100 [93, 108] | <0.001 |
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QRS, ms | 104 [94, 112] | 100 [92, 111] | 0.408 | 104 [92, 112] | 104 [92, 114] | 0.951 | 104 [96, 107] | 96 [92, 108] | 0.094 |
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PR, ms | 154 [139, 172] | 148 [136, 164] | 0.117 | 151 [136, 172] | 152 [138, 164] | 0.720 | 160 [146, 176] | 146 [133, 163] | 0.009 |
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QTc, ms | 430 [411, 445] | 426 [413, 441] | 0.441 | 428 [410, 442] | 427[414, 441] | 0.965 | 433 [416, 454] | 422 [410, 443] | 0.102 |
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Abnormal Q | 37 (28.03) | 19 (18.63) | 0.095 | 26 (25.49) | 10 (14.29) | 0.088 | 11 (36.67) | 9 (28.13) | 0.589 |
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TWI, % | 80 (60.61) | 61 (59.80) | 0.901 | 62 (60.78) | 41 (58.57) | 0.874 | 18 (60.00) | 20 (62.50) | >0.999 |
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RI, mv | 1.20 [0.80, 1.68] | 0.80 [0.50, 1.23] | <0.001 | 1.29 [0.80, 1.70] | 0.90 [0.50, 1.20] | 0.001 | 1.05 [0.70, 1.40] | 0.80 [0.60, 1.38] | 0.133 |
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RV1, mv | 0.31 [0.10, 0.70] | 0.40 [0.20, 0.80] | 0.535 | 0.31 [0.10, 0.70] | 0.40 [0.20, 0.80] | 0.267 | 0.35 [0.10, 0.70] | 0.55 [0.26, 1.20] | 0.055 |
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RV2, mv | 0.80 [0.30, 1.50] | 1.03 [0.52, 1.90] | 0.047 | 0.80 [0.30, 1.50] | 0.80 [0.50, 1.55] | 0.450 | 0.74 [0.29, 1.76] | 1.35 [0.81, 2.30] | 0.036 |
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RV3, mv | 1.75 [0.90, 2.60] | 1.45 [0.95, 2.50] | 0.523 | 1.65 [0.79, 2.60] | 1.35 [0.80, 2.50] | 0.457 | 2.23 [1.07, 2.70] | 1.95 [1.10, 2.40] | 0.587 |
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RV4, mv | 2.60 [1.74, 3.68] | 2.35 [1.39, 3.50] | 0.154 | 2.60 [1.72, 3.70] | 2.45 [1.38, 3.33] | 0.294 | 2.70 [1.93, 3.50] | 1.95 [1.39, 3.78] | 0.310 |
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RV5, mv | 2.70 [1.70, 3.55] | 2.35 [1.30, 3.36] | 0.072 | 2.61 [1.60, 3.70] | 2.60 [1.30, 3.35] | 0.210 | 2.85 [1.95, 3.21] | 1.71 [1.29, 3.39] | 0.178 |
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RV6, mv | 2.03 [1.40, 2.80] | 1.80 [1.10, 2.70] | 0.070 | 2.00 [1.30, 3.00] | 1.85 [1.08, 2.63] | 0.159 | 2.30 [1.64, 2.80] | 1.68 [1.16, 2.78] | 0.215 |
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RaVL, mv | 0.60 [0.38, 1.12] | 0.50 [0.20, 1.23] | 0.019 | 0.64 [0.40, 1.13] | 0.50 [0.20, 1.00] | 0.032 | 0.45 [0.33, 1.12] | 0.50 [0.23, 0.78] | 0.521 |
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SIII, mv | 0.30 [0.00, 0.79] | 0.30 [0.00, 0.70] | 0.595 | 0.30 [0.00, 0.72] | 0.30 [0.00, 0.70] | 0.685 | 0.41 [0.00, 0.85] | 0.30 [0.00, 0.72] | 0.622 |
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SV1, mv | 2.10 [1.40, 2.76] | 1.30 [0.92, 1.73] | <0.001 | 2.10 [1.40, 2.80] | 1.30 [0.90, 1.80] | <0.001 | 2.00 [1.25, 2.72] | 1.39 [1.03, 1.69] | 0.007 |
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SV2, mv | 2.30 [1.50, 3.17] | 1.90 [1.30, 2.50] | 0.008 | 2.30 [1.50, 3.11] | 1.85 [1.20, 2.50] | 0.029 | 2.35 [1.54, 3.83] | 2.00 [1.40, 2.48] | 0.128 |
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SV3, mv | 1.50 [0.68, 2.38] | 1.50 [0.80, 2.40] | 0.634 | 1.50 [0.70, 2.30] | 1.50 [0.78, 2.40] | 0.576 | 1.73 [0.44, 2.50] | 1.49 [0.93, 2.38] | 0.966 |
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SV4, mv | 0.90 [0.40, 1.78] | 1.03 [0.58, 1.90] | 0.135 | 0.90 [0.38, 1.53] | 1.20 [0.58, 1.90] | 0.084 | 0.85 [0.43, 2.03] | 0.95 [0.53, 1.64] | 0.933 |
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SV5, mv | 0.40 [0.10, 0.90] | 0.68 [0.30, 1.10] | 0.005 | 0.35 [0.00, 0.90] | 0.70 [0.30, 1.13] | 0.004 | 0.42 [0.20, 1.26] | 0.50 [0.30, 1.08] | 0.708 |
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SV6, mv | 0.20 [0.00, 0.40] | 0.30 [0.00, 0.60] | 0.018 | 0.20 [0.00, 0.30] | 0.25 [0.00, 0.60] | 0.030 | 0.27 [0.08, 0.53] | 0.30 [0.15, 0.59] | 0.645 |
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RV5SV1, mv | 4.58 [3.44, 6.16] | 3.50 [2.50, 4.91] | <0.001 | 4.60 [3.20, 6.30] | 3.55 [2.40, 4.95] | 0.001 | 4.58 [3.90, 5.81] | 3.35 [2.50, 4.93] | 0.010 |
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RⅠSⅢ, mv | 1.50 [1.00, 2.28] | 1.25 [0.70, 1.93] | 0.005 | 1.53 [1.00, 2.25] | 1.25 [0.68, 2.00] | 0.014 | 1.40 [1.00, 2.34] | 1.20 [0.80, 1.90] | 0.231 |
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RaVLSV3, mv | 2.30 [1.38, 3.19] | 2.30 [1.30, 2.86] | 0.598 | 2.30 [1.40, 3.06] | 2.30 [1.22, 2.90] | 0.711 | 2.23 [1.13, 3.79] | 2.20 [1.30, 2.80] | 0.688 |
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RV2V3, mv | 2.60 [1.40, 4.22] | 2.55 [1.50, 4.23] | 0.573 | 2.53 [1.40, 4.19] | 2.30 [1.40, 4.07] | 0.821 | 3.00 [1.41, 4.73] | 2.95 [2.23, 5.05] | 0.375 |
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SV2V3, mv | 3.95 [2.21, 5.16] | 3.50 [2.28, 4.80] | 0.186 | 3.85 [2.22, 4.90] | 3.55 [2.25, 4.80] | 0.377 | 4.68 [1.99, 5.63] | 3.48 [2.25, 4.80] | 0.254 |
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RV1V2, mv | 1.25 [0.44, 2.15] | 1.43 [0.90, 2.62] | 0.042 | 1.30 [0.43, 2.12] | 1.30 [0.70, 2.33] | 0.388 | 1.08 [0.43, 2.53] | 2.03 [1.13, 3.51] | 0.029 |
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SV1V2, mv | 4.46 [3.13, 5.70] | 3.20 [2.37, 4.13] | <0.001 | 4.37 [2.98, 5.83] | 3.30 [2.00, 4.45] | <0.001 | 4.48 [3.30, 5.48] | 3.20 [2.41, 3.99] | 0.005 |
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RV3V4, mv | 4.35 [2.62, 6.08] | 3.90 [2.30, 6.00] | 0.292 | 4.15 [2.58, 6.10] | 3.95 [2.18, 5.93] | 0.382 | 5.15 [3.11, 5.93] | 3.85 [2.50, 6.25] | 0.517 |
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SV3SV4, mv | 2.50 [0.99, 4.21] | 2.60 [1.39, 4.30] | 0.358 | 2.45 [1.06, 3.92] | 2.80 [1.30, 4.30] | 0.235 | 2.58 [0.82, 4.81] | 2.40 [1.45, 4.09] | 0.816 |
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Data are expressed as n (%) or median [25th and 75th percentiles].
TWI, T wave inversion; RV5SV1, amplitude of the R wave in V5 plus the S wave amplitude in V1; RⅠSⅢ, amplitude of the R wave in lead Ⅰ plus the S wave amplitude in lead Ⅲ; RaVLSV3, amplitude of the R wave in lead aVL plus the S wave amplitude in precordial lead V3; RV2V3, amplitude of the R wave in precordial lead V2 plus V3; SV2V3, amplitude of the S wave in precordial lead V2 plus V3. The rest set as the analogy.