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. Author manuscript; available in PMC: 2023 Aug 4.
Published in final edited form as: Alzheimers Dement. 2022 Apr 28;19(2):518–531. doi: 10.1002/alz.12675

Figure 4. Sex- and APOE-specific metabolic differential expression analysis.

Figure 4.

The significant P-value<0.05 of differentially produced metabolites are compared between patient groups to illustrate the specificity and commonality of AD-associated metabolic signatures to sex and APOE genotype. (A) Male vs Female; (B) APOEɛ4+ vs APOEɛ4-; (C) Male APOEɛ4+ vs Male APOEɛ4-; (D) Male APOEɛ4- vs Female APOEɛ4+; (E) Female APOEɛ4+ vs Female APOEɛ4-; (F) Male APOEɛ4+ vs Female APOEɛ4+; (G) Male APOEɛ4- vs Female APOEɛ4+; (H) Male APOEɛ4+ vs Female APOEɛ4-.