A. CONSORT diagram summarizing the endometrial cancer patients included in this study. B. Method employed for classification of endometrial cancers into the molecular subtypes using clinical MSK-IMPACT sequencing results and immunohistochemistry. C. Distribution of histologic subtypes and molecular subtypes for 1,834 endometrial cancers subjected to clinical sequencing. CN-H, copy number-high; CN-L, copy number-low; G1, grade 1; G2, grade 2; G3, grade 3; MSI-H, microsatellite instability-high; NOS, not otherwise specified.