Table 4.
Effect size of UHR on baPWV in prespecified and exploratory subgroup.
| Characteristic | No of participants | Effect size (95% CI) P | P for interaction |
|---|---|---|---|
| Sex | |||
| Male | 592 | 2.34 (−1.21, 5.89) .1970 | .0327 |
| Female | 320 | 11.97 (3.79, 20.15) .0042 | |
| Current smoker | |||
| No | 715 | 5.94 (2.06, 9.81) .0028 | .0452 |
| Yes | 197 | −1.41 (−7.57, 4.75) .6540 | |
| Ex-smoking | |||
| No | 462 | 8.38 (3.21, 13.54) .0015 | .0292 |
| Yes | 450 | 1.18 (−2.94, 5.30) .5744 | |
| Regular exercise (>1 wk) | |||
| No | 719 | 3.65 (0.02, 7.29) .0493 | .6190 |
| Yes | 177 | 1.60 (−5.77, 8.97) .6706 | |
| Fatty liver | |||
| No | 646 | 4.90 (0.56, 9.23) .0270 | .5343 |
| Yes | 265 | 2.87 (−2.01, 7.75) .2495 | |
| Menopausal status | |||
| Postmenopausal | 138 | −2.13 (−15.18, 10.92) .7495 | .0111 |
| No | 182 | 19.00 (8.50, 29.50) .0005 | |
| Alcohol consumption | |||
| <80 (g/wk) | 649 | 6.89 (2.85, 10.92) .0009 | .0103 |
| ≥80, <180 (g/wk) | 124 | 2.69 (−6.54, 11.93) .5676 | |
| ≥180 (g/wk) | 126 | −6.29 (−13.97, 1.40) .1093 | |
| BMI | |||
| <19 (kg/m2, mean ± SD) | 62 | 8.61 (−9.69, 26.90) .3566 | .7205 |
| ≥19, <26 (kg/m2, mean ± SD) | 700 | 4.77 (0.82, 8.73) .0183 | |
| ≥26 (kg/m2, mean ± SD) | 150 | 2.36 (−3.93, 8.66) .4621 | |
Adjusted: Sex; age; BMI; SBP; DBP; ALT; AST; γ-GTP; fatty liver status.
ALT = alanine aminotransferase, AST = aspartate transaminase, baPWV = brachial-ankle pulse wave velocity, BMI = body mass index, CI = confidence interval, DBP = diastole pressure, SBP = systolic pressure, UHR = uric acid to high-density lipoprotein cholesterol ratio.