TABLE 2.
Comparison of ICU Therapies in Patients With and Without COVID-19
| Characteristics | COVID-19 Negative (n = 398) | COVID-19 Positive (n = 206) | p |
|---|---|---|---|
| Time from intubation to tracheostomy (d) | 13.60 (8.66) | 15.90 (8.60) | 0.002 |
| Time from continuous sedation to tracheostomy (d) | 3.05 (5.23) | 0.95 (2.69) | < 0.001 |
| Time from antibiotics to tracheostomy (d) | 1.97 (3.71) | 2.45 (4.92) | 0.185 |
| Number of sedative agents since admission, mean (sd) | 3.22 (1.23) | 4.39 (1.18) | < 0.001 |
| Ventilator settings, mean (sd) | |||
| Fio2 at the time of tracheostomy (%) | 44.24 (12.96) | 53.28 (16.79) | < 0.001 |
| Positive end-expiratory pressure at the time of tracheostomy (mm Hg) | 5.69 (1.87) | 7.15 (2.71) | < 0.001 |
| Tidal volume at the time of tracheostomy (mL) | 412.40 (93.51) | 399.24 (83.38) | 0.093 |
| Blood gas, mean (sd) | |||
| Potential of hydrogen at the time of tracheostomy | 7.43 (0.07) | 7.41 (0.07) | 0.004 |
| Pco2 at the time of tracheostomy | 38.17 (10.24) | 45.81 (13.14) | < 0.001 |
Note—except where indicated, data are number of patients, with percentages in parentheses. Continuous variables are presented as means and sds for normally distributed data. Differences in distributions of characteristics of those with and those without COVID-19 were analyzed using Student t test. Boldface values indicate statistical significance (p < 0.05).