Table 5. Costa Rica's private sector - top 20 active ingredients in descending order of consumption - 2022 vs 2021.

DDD: Defined Daily Dose

Antibiotic	Costa Rica private sector		Change % year 2022 vs year 2021
	DDD x 1,000 inhabitants/day	Gross expenditure x 1,000 inhabitants/day	DDD x 1,000 €/day	Gross expenditure x 1,000 €/day
Amoxicillin	0.320	17.272	17.272	15.600
Amoxicillin and beta-lactamase inhibitor	0.904	20.938	20.938	21.066
Ampicillin	0.005	-0.412	-0.412	-0.534
Azithromycin	1.899	34.275	34.275	32.484
Aztreonam	0.005	-0.517	-0.517	-0.541%
Cefadroxil	0.051	1.312	1.312	1.355
Cefixime	0.153	13.069	13.069	12.654
Ceftriaxone	0.098	1.534	1.534	1.034
Cefuroxime	0.059	-0.636	-0.636	-0.750
Cephalexin	0.043	-0.117	-0.117 %	-1.347
Ciprofloxacino	0.176	-4.123	-4.123 %	-4.638
Clarithromycin	0.144	21.781	21.781	19.373
Clindamycin	0.018	-0.581	-0.581	-0.651
Doxycycline	1.791	0.899	0.899	1.003
Ertapenem	0.007	0.070	0.070	-0.026
Levofloxacin	0.494	11.389	11.389	7.730
Ofloxacin	0.029	0.030	0.030	0.009
Penicillin	0.004	-0.212	-0.212	-0.380
Sulfamethoxazole and trimethoprim	0.091	-0.885	-0.885	-0.801
Tetracycline	0.024	-0.148	-0.148	-0.158