Table 5:
Neurodevelopmental outcomes at 30 months of age in children with heterogenous critical congenital heart disease
| HLHS | TGA | Other | |||
|---|---|---|---|---|---|
| All | Genetic syndrome | No syndrome | |||
| Participants with BSID-II follow-up, n= | 11 | 54 | 14 | 4 | 10 |
| Age at follow-up, years, median (IQR) | 2.6 (2.5-2.7) | 2.6 (2.5-2.7) | 2.7 (2.6-2.9) | 2.7 (2.7-2.8) | 2.7 (2.6-3.0) |
| p= | 0.042 | 0.515 | |||
| Mental Developmental Index, median (IQR) | 95.0 (81.5-96.0) | 93.5 (84.0-104.0) | 82.5 (67.0-88.0) | 58.5 (50.0-75.5) | 85.0 (81.0-101.0) |
| p= | 0.035 | 0.047 | |||
| Normal, n= (%) | 7 (64%) | 40 (74%) | 5 (36%) | 0 (0%) | 5 (50%) |
| Mild-moderate, n= (%) | 2 (18%) | 13 (24%) | 5 (36%) | 1 (25%) | 4 (40%) |
| Severe, n= (%) | 2 (18%) | 1 (2%) | 4 (29%) | 3 (75%) | 1 (10%) |
| Psychomotor Developmental Index, median (IQR) | 77.0 (71.5-83.5) | 91.0 (84.0-102.0) (n=52) | 85.5 (76.0-98.0) | 54.5 (50.0-68.0) | 91.5 (83.0-98.0) |
| p= | 0.008 | 0.007 | |||
| Normal, n= (%) | 3 (27%) | 39 (75%) | 7 (50%) | 0 (0%) | 7 (70%) |
| Mild-moderate, n= (%) | 6 (55%) | 10 (19%) | 4 (29%) | 1 (25%) | 3 (30%) |
| Severe, n= (%) | 2 (18%) | 3 (6%) | 3 (21%) | 3 (75%) | 0 (0%) |