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. 2023 Jun 28;81(3):579–591. doi: 10.1007/s12020-023-03422-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Representative 2D images of L4 and the femur (A, B). The measurements areas of cortical and trabecular bone in femur and L4 are surrounded by red lines for the Non-Orx groups. 2D analysis of L4 (C–E) and femur (F–H) performed 18 weeks after Orx in Non Orx rats and Orx rats either untreated or treated with ostarine or testosterone. a: differs from Non Orx; b: differs from Orx; c: differs from Ostarine Therapy group; d:differs from Ostarine Proph. Group, (p < 0.05, Tukey–test)