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. 2023 Jun 28;81(3):579–591. doi: 10.1007/s12020-023-03422-7

Table 1.

Starting and average bodyweight, organ weight at the end of the study and in vivo pQCT data of L4

Group Non-Orx Orx Ostarine Therapy Ostarine Proph. Test. Therapy Test. Proph.
Mean SD Mean SD Mean SD Mean SD Mean SD Mean SD
Starting body weight [g]# 717.5 70.5 713.3 75.3 687.9 81.7 715.8 71.2 680.2 74.3 703.4 82.3
Average body weight [g]§ 730.2 29.6 669.5a 34.9 667.1a 33.5 683.7a 30.3 679.6a 25.3 663.7a 31.9
Prostate weight [g] 1.22 0.30 0.18a,d 0.07 0.39a 0.08 0.62a,b,e,f 0.13 0.19a 0.07 0.33a 0.13
Heart weight [g] 1.75 0.22 1.68 0.15 1.84 0.32 1.84 0.31 1.70 0.31 1.65 0.17
Liver weight [g] 23.1 3.9 19.7 2.4 20.5 1.9 20.7 5.2 20.1 0.5 20.8 2.9
Kidney weight [g] 4.0 0.6 3.5 0.5 3.9 0.6 4.2 0.5 3.3 0.2 3.5 0.6
Spleen weight [g] 1.40 0.23 1.46 0.15 1.35 0.28 1.55 0.27 1.33 0.14 1.58 0.44

Total BMD [mg/ccm]

12 weeks

535.0 46.53 476.2a 35.49 489.4 37.06 557.7b,c 50.23 493.3d 40.0 529.9b 49.54

Total BMD

[mg/ccm]

18 weeks

475.3 32.38 430.2a 38.16 472.6 50.80 526.8a,b,c 46.11 465.5d 39.9 485.3b 23.91

aDiffers from Non-Orx, bdiffers from Orx, cdiffers from Ostarine Therapy group, ddiffers from Ostarine Proph. group, ediffers from Test. Therapy group, fdiffers from Test. Proph. Group, (p > 0.05, Tukey-test)  

#Published in [23]

§Published in [22]