Table 1.
Group | Non-Orx | Orx | Ostarine Therapy | Ostarine Proph. | Test. Therapy | Test. Proph. | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
Starting body weight [g]# | 717.5 | 70.5 | 713.3 | 75.3 | 687.9 | 81.7 | 715.8 | 71.2 | 680.2 | 74.3 | 703.4 | 82.3 |
Average body weight [g]§ | 730.2 | 29.6 | 669.5a | 34.9 | 667.1a | 33.5 | 683.7a | 30.3 | 679.6a | 25.3 | 663.7a | 31.9 |
Prostate weight [g]#§ | 1.22 | 0.30 | 0.18a,d | 0.07 | 0.39a | 0.08 | 0.62a,b,e,f | 0.13 | 0.19a | 0.07 | 0.33a | 0.13 |
Heart weight [g] | 1.75 | 0.22 | 1.68 | 0.15 | 1.84 | 0.32 | 1.84 | 0.31 | 1.70 | 0.31 | 1.65 | 0.17 |
Liver weight [g] | 23.1 | 3.9 | 19.7 | 2.4 | 20.5 | 1.9 | 20.7 | 5.2 | 20.1 | 0.5 | 20.8 | 2.9 |
Kidney weight [g] | 4.0 | 0.6 | 3.5 | 0.5 | 3.9 | 0.6 | 4.2 | 0.5 | 3.3 | 0.2 | 3.5 | 0.6 |
Spleen weight [g] | 1.40 | 0.23 | 1.46 | 0.15 | 1.35 | 0.28 | 1.55 | 0.27 | 1.33 | 0.14 | 1.58 | 0.44 |
Total BMD [mg/ccm] 12 weeks |
535.0 | 46.53 | 476.2a | 35.49 | 489.4 | 37.06 | 557.7b,c | 50.23 | 493.3d | 40.0 | 529.9b | 49.54 |
Total BMD [mg/ccm] 18 weeks |
475.3 | 32.38 | 430.2a | 38.16 | 472.6 | 50.80 | 526.8a,b,c | 46.11 | 465.5d | 39.9 | 485.3b | 23.91 |