Table 2.
Genes involved in immune cell activation upregulated in Saha-CATH3, 4 and 6 treatments.
| Function | Gene | Cathelicidin | Fold change | False discovery rate |
|---|---|---|---|---|
| Cytokine | IL6 | Saha-CATH3 | 4.38 | 0.0019 |
| Cytokine | IL6 | Saha-CATH4 | 3.73 | 0.0050 |
| Cytokine | IL6 | Saha-CATH6 | 11.14 | 1.02E-06 |
| Cytokine receptor | IL6R | Saha-CATH3 | 2.88 | 4.56E-06 |
| Cytokine receptor | IL6R | Saha-CATH4 | 5.25 | 3.62E-10 |
| Cytokine receptor | IL6R | Saha-CATH6 | 1.70 | 0.012 |
| Immune signaling | MYD88 | Saha-CATH3 | 2.64 | 4.57E-11 |
| Immune signaling | MYD88 | Saha-CATH4 | 4.15 | 2.01E-15 |
| Immune signaling | MYD88 | Saha-CATH6 | 1.78 | 9.77E-07 |
| Transcription factor | RUNX1 | Saha-CATH3 | 2.71 | 2.58E-07 |
| Transcription factor | RUNX1 | Saha-CATH4 | 2.43 | 1.46E-06 |
| Transcription factor | RUNX1 | Saha-CATH6 | 1.61 | 0.0046 |
| Cytokine receptor | IL1R1 | Saha-CATH3 | 2.41 | 0.00031 |
| Cytokine receptor | IL1R1 | Saha-CATH6 | 2.29 | 0.00045 |
| Cytokine receptor | IL21R | Saha-CATH6 | 1.58 | 0.0019 |