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. 2023 Aug 4;8:109. doi: 10.1038/s41541-023-00706-x

Fig. 1. The therapeutic effect of Ad-CAIX/Ad-PD-L1 in the hCAIX-Renca subcutaneous tumor model.

Fig. 1

a Schematic diagram of the subcutaneous hCAIX-Renca tumor model by intramuscular injection of various vaccines on the 7th day after tumor inoculation. b The volume of subcutaneous tumors was measured weekly to evaluate tumor progression. c Tumor volumes of each group were measured 42 days post tumor inoculation. d Tumor weights of each group were measured at the experimental endpoint. e, f The percentages and total numbers of T cells, CD8+ T cells, CD4+ T cells, NK cells, DCs, and macrophages in TILs from tumors of immunized mice in each group. The data shown are the representative of three experiments. Data are shown as mean ± SD. The different significance was set at *p < 0.05, **p < 0.01, and ***p < 0.001; ns not significant. Multiple groups of comparison data were analyzed by one-way ANOVA.