Fig. 8.

(A) Self-assembled phytochemical complex with naturally-occurring modality in Huang-Lian-Jie-Du decoction. Reproduced with permission from Ref. [194]. Copyright 2021, Elsevier Publishing Group; (B) Illustration of promotion mechanisms of particle aggregates in Coptis chinensis decoction on absorption of berberine in small intestine. Reproduced with permission from Ref. [198]. Copyright 2020, The Royal Society of Chemistry; (C) Scheme of immune efficacy of herbal decoction based on nano-aggregate particles. Reproduced with permission from Ref. [201]. Copyright 2018, Elsevier Publishing Group; (D) Formation of nano-aggregate particles in boiling Isatis indigotica decoction. Reproduced with permission from Ref. [202]. Copyright 2017, Elsevier Publishing Group.