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. 2023 Aug 4;4(8):e232310. doi: 10.1001/jamahealthforum.2023.2310

Table 3. Secondary Transmission and Exposure Characteristics, Fall 2021 (Univariable Analysis).

Exposure No. of students, faculty, and staffa SAR, % Fisher exact P value
Index cases Contacts Contacts tested No in-school transmission In-school transmission
Contact role
Staff 37 107 107 107 0 0 .07
Student 207 1566 1487 1443 44 3.0
Contact grade level and staff
Prekindergarten, kindergarten, and elementaryb 143 940 888 847 41 4.6 <.001
Middle schoolc 44 381 374 372 2 0.5
High schoold 24 237 220 219 1 0.5
Staff 37 107 107 107 0 0
Not available 4 8 5 5 0 0
Classroom exposure
No 132 497 485 479 6 1.2 .01
Yes 187 1176 1109 1071 38 3.4
Lunch exposure
No 207 1294 1218 1180 38 3.1 .15
Yes 106 379 376 370 6 1.6
Sports exposure
No 214 1658 1580 1536 44 2.8 >.99
Yes 2 15 14 14 0 0
Distance during exposure, ft
<3 168 1214 1203 1174 29 2.4 .003
<6 (Not specified) 13 72 68 68 0 0
3-6 35 177 116 115 1 0.9
Unknown 37 210 207 193 14 6.8
Masking during exposure
Both case and contact masked 172 1042 970 948 22 2.3 .003
Case masked and contact unmasked 4 8 8 8 0 0
Neither masked 109 411 407 400 7 1.7
Unknown 33 212 209 194 15 7.2
Quarantine/testing approach
TTS 186 1110 1110 1079 31 2.8 <.001
Quarantine 36 73 64 58 6 9.4
Vaccinated; tested on day 3-5 55 350 350 350 0 0
Other 19 77 10 9 1 10.0
Contact vaccination status
Fully vaccinated 65 410 398 398 0 0 <.001
Partially vaccinated 22 66 57 54 3 5.3
Unvaccinated 194 1183 1128 1087 41 3.6
Index case role
Staff 21 200 162 161 1 0.6 .12
Student 194 1473 1432 1389 43 3.0
Index case grade level and staff
Prekindergarten, kindergarten, and elementaryb 131 869 843 804 39 4.6 <.001
Middle schoolc 42 388 379 376 3 0.8
High schoold 21 216 210 209 1 0.5
Staff 21 200 162 161 1 0.6
Means of identifying index case
In-school close contact, enrolled in TTS program 7 52 52 51 1 1.9 .55
In-school close contact, not enrolled in TTS program 1 2 2 2 0 0
Out-of-school contact 51 375 373 361 12 3.2
School-based asymptomatic testing program 46 265 261 251 10 3.8
Tested because of symptoms 109 969 896 875 21 2.3
Index case symptoms
No 74 526 520 501 19 3.7 .14
Yes 141 1147 1074 1049 25 2.3
Index case vaccination status
Fully vaccinated 32 347 319 318 1 0.3 .001
Partially vaccinated 6 52 51 51 0 0
Unvaccinated 176 1263 1213 1170 43 3.5
SVI overall quartilee
<0.25 (Lowest) 67 498 498 482 16 3.2 .63
0.25-0.5 (Highest) 138 1115 1037 1009 28 2.7
SVI SES quartilee
<0.25 (Lowest) 173 1435 1360 1330 30 2.2 <.001
0.25-0.5 (Highest) 32 178 175 161 14 8.0

Abbreviations: SAR, secondary attack rate (calculated as [probable and possible transmissions / contacts tested] × 100); SES, socioeconomic status; SVI, Social Vulnerability Index; TTS, test to stay.

a

Unknown or missing values were removed if the number of unknown or missing values comprised less than 5% of the total number of contacts tested for each exposure category.

b

Grades 1 through 5.

c

Grades 6 through 8.

d

Grades 9 through 12.

e

Overall quartiles as found in the school districts included in the study.