Table 4.
Risk of All-Cause Mortality, Cardiovascular Mortality and Hospitalization for Heart Failure in Young Patients With AMI-CS
| Cohort | Univariate |
Multivariatea |
||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| All-cause mortality | ||||
| Full cohort | 3.84 (2.78−5.30) | <0.001 | 2.20 (1.40−3.44) | 0.001 |
| Matched cohortb | 4.40 (2.89−6.70) | <0.001 | 2.84 (1.68−4.81) | <0.001 |
| Full cohort that survived to hospital discharge | 1.77 (1.09−2.87) | 0.021 | 1.54 (0.83−2.85) | 0.170 |
| Matched cohort that survived to hospital discharge | 2.21 (1.26−3.89) | 0.006 | 1.70 (0.86−3.35) | 0.125 |
| Cardiovascular Mortality | ||||
| Full cohort | 6.09 (4.24−8.73) | <0.001 | 3.13 (1.88−5.21) | <0.001 |
| Matched cohort | 6.80 (4.09−11.32) | <0.001 | 4.09 (2.17−7.71) | <0.001 |
| Full cohort that survived to hospital discharge | 2.67 (1.55−4.58) | <0.001 | 2.29 (1.13−4.66) | 0.022 |
| Matched cohort that survived to hospital discharge | 3.52 (1.79−6.89) | <0.001 | 2.76 (1.21−6.30) | 0.016 |
| One-Year Hospitalization for Heart Failure | ||||
| Full cohort | 4.34 (2.20−8.57) | <0.001 | 5.40 (2.42−12.07) | <0.001 |
| Matched cohort | 5.62 (2.08−15.22) | 0.001 | 5.99 (2.04−17.61) | 0.001 |
| Full cohort that survived to hospital discharge | 4.30 (2.12−8.72) | <0.001 | 5.57 (2.39−12.95) | <0.001 |
| Matched cohort that survived to hospital discharge | 5.37 (1.95−14.78) | 0.001 | 6.18 (2.04−18.78) | 0.001 |
a
Multivariate analyses adjusted for age, sex, ADI, STEMI, OHCA, DM, HTN, dyslipidemia, tobacco use, cocaine use, cardiac catheterization, presentation creatinine, standardized troponin.
b
Matched for age, sex, race, HTN, smoking status, left main coronary artery disease, STEMI.ADI, area deprivation index; DM, diabetes mellitus; HTN, hypertension; OHCA, out-of-hospital cardiac arrest; STEMI, ST elevation myocardial infarction.