TABLE 3.
bDMARD and csDMARD Treatment Patterns by bDMARD Fill Status
| All Patients (N = 373) | Early Biologic Fillersa(n = 170) | Late Biologic Fillersb(n = 59) | Nonfillersc(n = 144) | Late Biologic Fillers and Nonfillers Combined (n = 203) | |
|---|---|---|---|---|---|
| Index bDMARD, n (%) | |||||
| TNFi | 331 (88.7) | 154 (90.6) | 53 (89.8) | 124 (86.1) | 177 (87.2) |
| Non-TNFi biologic | 42 (11.3) | 16 (9.4) | 6 (10.2) | 20 (13.9) | 26 (12.8) |
| csDMARD use, n (%) | |||||
| Any | 235 (63.0) | 128 (75.3) | 45 (76.3) | 62 (43.1) | 107 (52.7) |
| Days -1 to 180 pre-index | 216 (57.9) | 121 (71.2) | 38 (64.4) | 57 (39.6) | 95 (46.8) |
| Days 0 to 30 post-index | 135 (36.2) | 78 (45.9) | 22 (37.3) | 35 (24.3) | 57 (28.1) |
| Days 31 to 180 post-index | 187 (50.1) | 100 (58.8) | 36 (61.0) | 51 (35.4) | 87 (42.9) |
| Any injectable biologic DMARD during days 31-180 post-index, n (%) | |||||
| Yes | 207 (55.5) | 148 (87.1) | 59 (100.0) | 0 | 59 (29.1) |
| No | 166 (44.5) | 22 (12.9) | 0 | 144 (100.0) | 144 (70.9) |
abDMARD prescription filled within 30 days of index bDMARD.
bbDMARD prescription filled within 31-180 days of index bDMARD.
cbDMARD prescription not filled at all within 180 days of index bDMARD.
bDMARD = biologic disease-modifying antirheumatic drug; csDMARD = conventional synthetic disease-modifying antirheumatic drug; TNFi = tumor necrosis factor inhibitor.