Table 4.
Univariable and multivariable logistic regression analyses regarding primary outcomes within the propensity score-matched cohort (n = 417)
Primary outcomes | ||||||
---|---|---|---|---|---|---|
Univariable model | Multivariable model* corrected for the influence of both centers |
|||||
Potential predictors of outcome/confounders (as identified in Table 1 and as established in the literature) |
OR | 95% CI | p value | OR | 95% CI | p value |
Return to premorbid neurologic function | ||||||
Female sex | 0.62 | 0.46–0.84 | 0.002 | 0.48 | 0.33–0.68 | < 0.001 |
Age (per every additional year of age) | 0.97 | 0.96–0.98 | < 0.001 | 0.97 | 0.96–0.98 | < 0.001 |
Acute intracranial hemorrhage | 0.07 | 0.03–0.16 | < 0.001 | 0.07 | 0.03–0.15 | < 0.001 |
SE severity (as quantified by the STESS) | 0.44 | 0.33–0.61 | < 0.001 | 0.99 | 0.62–1.56 | 0.949 |
SE type | 0.89 | 0.72–1.09 | 0.262 | 0.90 | 0.70–1.16 | 0.406 |
In-hospital death | ||||||
Female sex | 2.34 | 1.20–4.59 | 0.013 | 2.00 | 0.93–4.26 | 0.074 |
Age (per every additional year of age) | 1.04 | 1.02–1.07 | < 0.001 | 1.04 | 1.01–1.07 | 0.005 |
Acute intracranial hemorrhage | 1.15 | 0.47–2.82 | 0.753 | 1.05 | 0.41–2.70 | 0.913 |
SE severity (as quantified by the STESS) | 3.59 | 1.57–8.20 | 0.002 | 1.55 | 0.55–4.37 | 0.403 |
SE type | 1.92 | 1.26–2.94 | 0.003 | 1.95 | 1.24–3.07 | 0.004 |
Death at 30 days follow-up | ||||||
Female sex | 1.05 | 0.75–1.46 | 0.788 | 0.74 | 0.49–1.10 | 0.136 |
Age (per every additional year of age) | 1.04 | 1.02–1.05 | < 0.001 | 1.06 | 1.04–1.07 | < 0.001 |
Acute intracranial hemorrhage | 0.96 | 0.58–1.58 | 0.866 | 0.65 | 0.38–1.13 | 0.124 |
SE severity (as quantified by the STESS) | 1.73 | 1.22–2.46 | 0.002 | 0.45 | 0.27–0.76 | 0.003 |
SE type | 1.65 | 1.30–2.10 | < 0.001 | 2.19 | 1.65–2.89 | < 0.001 |
OR = odds ratio; CI = confidence interval; SE = status epilepticus; STESS = status epilepticus severity score
*All Hosmer–Lemeshow goodness-of-fit tests insignificant indicating adequate model fit
Bold font indicates statistical significance (with a p value set at 0.05)