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SPT16 depletion alters mRNA transcription and abundance, with most prominent effects after 12 + h of depletion
| Hours depleted | 0 | 3 | 6 | 12 | 12 + 24-h washout | 24 | 24 [RNA-seq] |
|---|---|---|---|---|---|---|---|
| mRNAs up | 3 | 58 | 214 | 1366 | 1815 | 5398 | 3977 |
| mRNAs down | 53 | 5 | 174 | 1932 | 1427 | 5000 | 3781 |
Control samples and SPT16-depleted samples were separately pooled between cell lines for downstream analyses. Only transcripts with an adjusted p-value of < 0.05 are displayed (analyzed with DESeq2)
