Table 2.
Overlap between SPT16-V5 CUT&RUN peaks and OCT4, SOX2, and NANOG ChIP-seq peaks
| Peak overlap category | OCT4 peaks | Sox2 Peaks | Nanog Peaks | Any of OSN |
|---|---|---|---|---|
| V5 Peaks | 8544 | 5948 | 5307 | 9682 |
| OSN Peaks | 45,476 | 19,211 | 16,817 | 52,899 |
| % of OSN peaks bound by FACT | 18.33% | 30.72% | 31.40% | 17.91% |
| % of V5 peaks bound by OSN | 52.41% | 36.85% | 32.94% | 59.63% |
| V5-bound promoters | 4261 | 2719 | 2327 | 4452 |
| OSN-bound promoters | 6550 | 1542 | 666 | 6948 |
| V5- and OSN-bound promoters | 2040 | 801 | 343 | 2202 |
| OSN-bound TSS-distal peaks | 38,926 | 17,669 | 16,151 | 45,938 |
| V5-bound TSS-distal OSN peaks | 6504 | 5147 | 4964 | 7480 |
To be called as overlapping, peaks must have directly shared at least 1 bp and passed peak-calling thresholds (see “Methods”)