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. 2023 Aug 5;18:573. doi: 10.1186/s13018-023-03980-6

Table 3.

Indicators of the classification and medical tests to identify the cause of lower limb swelling after TKA

Primary indicators: causes of swelling Secondary and tertiary indicators: measurement indicators Reasonableness score (x ± s, points) Coefficient of variation (CV)
1. Inflammation response 4.82 ± 0.39 0.08
1.1 Blood tests: routine blood test 4.73 ± 0.45 0.09
1.1.1 Leukocyte count 4.45 ± 0.78 0.18
1.1.2 Neutrophil count 4.55 ± 0.66 0.14
1.1.3 Platelet count 4.82 ± 0.39 0.08
1.2 Blood test: C-reactive protein (CRP) 4.82 ± 0.39 0.08
1.3 Blood test: erythrocyte sedimentation rate (ESR) 4.64 ± 0.64 0.14
1.4 Blood test: Calcitoninogen (PCT) 4.36 ± 0.48 0.11
1.5 Blood test: amyloid A (SAA) 4.09 ± 0.90 0.22
1.6 Blood test: Interleukin 1β 4.27 ± 0.75 0.18
1.7 Blood test: interleukin 6 4.27 ± 0.75 0.18
2. Poor venous return 4.82 ± 0.39 0.08
2.1 Blood test: D-dimer + FDP 4.82 ± 0.39 0.08
2.2 Blood test: blood routine (platelet count) 4.82 ± 0.39 0.08
2.3 Blood test: four coagulation functions (APTT + PT + FG + TT) 4.64 ± 0.48 0.10
2.4 Color Doppler ultrasound scan: common iliac vein 4.45 ± 0.78 0.18
 2.4.1 Maximum blood flow rate 4.36 ± 0.88 0.20
 2.4.2 Whether under pressure 4.45 ± 0.78 0.18
2.5 Color Doppler ultrasound scan: common femoral vein 4.64 ± 0.77 0.17
 2.5.1 Blood flow velocity 4.36 ± 1.07 0.24
 2.5.2 Peak velocity of blood flow 4.45 ± 0.78 0.18
 2.5.3 Average velocity of blood flow 4.27 ± 1.05 0.25
 2.5.4 Diameter 4.45 ± 0.89 0.20
 2.5.5 Blood flow 4.18 ± 0.94 0.22
 2.5.6 Thrombus 4.55 ± 0.66 0.14
2.6 Ultrasound scan: popliteal vein 4.73 ± 0.62 0.13
 2.6.1 Internal diameter 4.36 ± 0.88 0.20
 2.6.2 Thrombus 4.64 ± 0.64 0.14
2.7 Ultrasound scan: superficial femoral vein 4.64 ± 0.77 0.17
 2.7.1 Internal diameter 4.45 ± 0.89 0.20
 2.7.2 Time, diameter, and regurgitation velocity of the first pair of valves in the superficial femoral vein during calm respiratory state and ValsalVa action 4.45 ± 0.99 0.22
 2.7.3 Thrombus 4.64 ± 0.64 0.14
2.8 Ultrasound scan: deep femoral vein 4.64 ± 0.77 0.17
 2.8.1 Backflow signal 4.45 ± 0.89 0.20
 2.8.2 Backflow time 4.45 ± 0.89 0.20
3 Joint hematoma 4.55 ± 0.78 0.17
3.1 Ultrasound scan 4.27 ± 0.75 0.18
4 Muscle injury and healing 4.27 ± 0.75 0.18
4.1 Ultrasound scan: quadriceps muscle 4.27 ± 0.75 0.18
 4.1.1 Thickness of the rectus femoris, middle femoris, and medial femoris muscles 4.09 ± 0.79 0.19
4.2 Blood test: serum myoglobin 3.91 ± 0.79 0.20
4.3 Blood test: serum creatine kinase 3.91 ± 0.79 0.20