Table 1.
Baseline characteristics of the study population
| Grip strength at the dominant hand | Grip strength at the non-dominant hand | |||||||
|---|---|---|---|---|---|---|---|---|
| Women | Men | P values | Overall | Women | Men | P values | Overall | |
| N = 603 (61.8%) | N = 373 (38.2%) | N = 976 | N = 600 (61.4%) | N = 377 (38.6%) | N = 977 | |||
| Age, mean (SD), years | 75.2 (4.5) | 75.4 (4.8) | 0.45 | 75.2 (4.6) | 75.1 (4.5) | 75.4 (4.8) | 0.35 | 75.2 (4.6) |
| Age groups, N (%) | ||||||||
| ≤ 75 years | 367 (60.9) | 221 (59.2) | 0.62 | 588 (60.2) | 366 (61.0) | 223 (59.1) | 0.57 | 589 (60.3) |
| > 75 years | 236 (39.1) | 152 (40.8) | 388 (39.8) | 234 (39.0) | 154 (40.9) | 388 (39.7) | ||
| Height, mean (SD), m | 1.6 (0.1) | 1.7 (0.1) | < .001 | 1.6 (0.1) | 1.6 (0.1) | 1.7 (0.1) | < .001 | 1.7 (0.1) |
| Weight, mean (SD), kg | 65.4 (12.0) | 78.3 (11.6) | < .0001 | 70.3 (13.4) | 65.5 (11.9) | 78.4 (11.8) | 70.5 (13.4) | |
| BMIb, mean (SD), kg/m2 | 25.5 (4.5) | 26.3 (3.6) | 0.003 | 25.8 (4.2) | 25.5 (4.5) | 26.3 (3.6) | 0.002 | 25.8 (4.2) |
| SPPB scorec, median (IQR) | 12.0 (11.0–12.0) | 12.0 (11.0–12.0) | 0.004 | 12.0 (11.0–12.0) | 12.0 (11.0–12.0) | 12.0 (11.0–12.0) | 0.005 | 12.0 (11.0–12.0) |
| Gait speed, mean (SD), m/s | 1.1 (0.2) | 1.1 (0.2) | 0.23 | 1.1 (0.2) | 1.1 (0.2) | 1.1 (0.2) | 0.16 | 1.1 (0.2) |
| 5 times sit-to-stand test, mean (SD) | 11.0 (3.0) | 10.5 (3.0) | 0.006 | 10.8 (3.0) | 11.0 (3.0) | 10.5 (3.0) | 0.004 | 10.8 (3.0) |
| Study centers, N (%) | ||||||||
| Basel | 146 (24.2) | 89 (23.9) | 0.57 | 235 (24.1) | 147 (24.5) | 94 (24.9) | 0.48 | 241 (24.7) |
| Geneva | 127 (21.1) | 69 (18.5) | 196 (20.1) | 127 (21.2) | 68 (18.0) | 195 (20.0) | ||
| Zurich | 330 (54.7) | 215 (57.6) | 545 (55.8) | 326 (54.3) | 215 (57.0) | 541 (55.4) | ||
| Prevalence of impaired function | ||||||||
| Gait speed < 0.8 m/s (n, %) | 50 (8.3) | 24 (6.5) | 0.29 | 74 (7.6) | 49 (8.2) | 24 (6.4) | 0.30 | 73 (7.5) |
| Gait speed < 1.0 m/s (n, %) | 180 (29.9) | 119 (32.0) | 0.49 | 299 (30.7) | 181 (30.2) | 119 (31.7) | 0.64 | 300 (30.8) |
| Slow 5TSTS > 11.19 s | 235 (39.6) | 126 (33.9) | 0.08 | 361 (37.4) | 235 (39.8) | 127 (33.8) | 0.06 | 362 (37.4) |
| Present sarcopeniad (n, %) | 25 (7.6) | 45 (21.0) | < .001 | 70 (12.9) | 24 (7.4) | 46 (21.5) | < .001 | 70 (13.0) |
Medians and IQRs are presented for variables with skewness > 1.5. Percentages are rounded to 1 decimal, which could lead to percentage sums of 100.1% or 99.9%. b Body mass index (BMI) was calculated as weight in kilograms divided by height in meters squared. c The Short Physical Performance Battery (SPPB) assesses lower extremity function. Scores range from 0 to 12, in which higher scores are better, d Baumgartner definition (RSMI), only assessed at Zurich