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. 2023 Aug 4;22:201. doi: 10.1186/s12933-023-01944-y

Table 3.

LV geometry and function of the study population

Non-DM (n = 143) Non-insulin-treated DM (n = 156) Insulin-treated DM (n = 78)
LVEDV, mL 259.1 (202.7, 320.5) 267.3 (197.2, 312.9) 282.2 (210.8, 351.5) &#
LVEDV index, mL/m2 155.1 ± 42.6 153.4 ± 48.8 173.6 ± 69.5*†
LVESV, mL 189.8 (137.1, 252.6) 193.8 (137.8, 247.1) 211.7 (149.7, 284.7) &#
LVESV index, mL/m2 117.7 ± 41.0 116.2 ± 45.9 131.3 ± 63.7
LVSV, mL 62.9 ± 22.9 61.5 ± 23.8 71.1 ± 26.9*†
LVSV index, mL/m2 37.4 ± 10.9 36.1 ± 10.1 40.9 ± 12.7
LVEF, % 25.7 ± 8.6 25.2 ± 9.0 25.2 ± 9.2
LVM, g 127.4 ± 37.1 145.4 ± 39.8* 164.2 ± 36.2*†
LVM index, g/m2 76.6 ± 20.7 83.5 ± 24.6* 92.7 ± 16.8*†
LVEDD, mm 64.3 ± 6.7 64.7 ± 6.1 65.2 ± 6.3
LVESD, mm 51.3 ± 4.4 52.0 ± 5.6 50.5 ± 5.9
LV length, mm 96.7 ± 12.1 97.3 ± 11.2 100.2 ± 10.8
3D-SI 0.55 ± 0.13 0.57 ± 0.14 0.63 ± 0.15*†

Data are presented as mean ± SD, or media (Q1–Q3).

One-way analysis of variance test: * P-value < 0.017 versus no DM cohort. † P-value < 0.017 versus DM not on insulin cohort. Kruskal-Wallis test: & P-value < 0.05 versus no DM cohort. # P-value < 0.05 versus DM not on insulin cohort

Abbreviations: LV, left ventricular; DM, diabetes mellitus; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVSV, left ventricular stroke volume; LVEF, left ventricular ejection fraction; LVM, left ventricular mass; LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; 3D-SI, three-dimensional spherical index