Table 4.

Linear regression analysis of the determination of impaired LV contractile function in overall cohort

	Circumferential PS		Longitudinal PS
	Univariable β	Multivariable β	Univariable β	Multivariable β
Age, per 10 units increase	0.06		0.02
Obesity#, yes or no	0.18†	0.20†	0.20†	0.12*
HT, yes or no	0.04		0.22†
CAD, yes or no	0.07		0.19†	0.15†
T2DM, yes or no	0.12*	0.10*	0.34†	0.18†
Insulin use, yes or no	0.20†	0.16†	0.28†	0.13*
NT-proBNP§, per 1 unit increase	0.20†	0.19†	0.23†	0.17†
eGFR, per 1 unit increase	-0.06		-0.11*
Indexed LVM, per 1 unit increase	0.20†	0.16†	0.26†	0.18†

β is adjusted regression coefficient

* P-value < 0.05. † P-value < 0.01

# Subjects with body mass index ≥ 25 kg/m² were classified as obese group that proposed by the World Health Organization for Asian populations

§ NT-proBNP is log-transformed before being included in the regression analysis

Abbreviations: LV, left ventricular; PS, peak strain; HT, hypertension; CAD, coronary artery disease; DM, diabetes mellitus; NT-proBNP, amino-terminal pro-B-type natriuretic peptide; eGFR, estimated glomerular filtration rate; LVM, left ventricular mass