Table 4.
Univariate and Multivariate Logistic Regression of Predictors of Adherence to National Comprehensive Cancer Network Treatment Guidelines Among Patients With Endometrial Carcinoma Between 2006 and 2015 in the SEER (Surveillance, Epidemiology, and End Results) Database (N=83,883)
| Model 1 |
Model 2 |
Model 3 |
|
|---|---|---|---|
| Characteristic | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
|
| |||
| Race-ethnicity | |||
| White | Referent | Referent | |
| Black | 0.88 (0.83–0.92)* | 0.89 (0.84–0.94)* | |
| Latina | 0.79 (0.75–0.82)* | 0.92 (0.88–0.96)* | |
| Asian | 1.08 (1.03–1.15)† | 1.14 (1.08–1.21)* | |
| Native Hawaiian or Pacific Islander | 1.01 (0.89–1.15) | 1.19 (1.04–1.35)† | |
| American Indian or Alaska Native | 0.73 (0.62–0.87)* | 0.82 (0.69–0.98)† | |
| Neighborhood SES | |||
| Highest | Referent | Referent | |
| High-middle | 0.89 (0.85–0.93)* | 0.89 (0.86–0.93)* | |
| Middle | 0.83 (0.80–0.87)* | 0.84 (0.80–0.88)* | |
| Low-middle | 0.80 (0.77–0.83)* | 0.82 (0.78–0.86)* | |
| Lowest | 0.73 (0.70–0.76)* | 0.73 (0.69–0.77)* | |
| Age at diagnosis (y) | |||
| Younger than 54 | Referent | ||
| 54–61 | 1.37 (1.32–1.43)* | ||
| 62–68 | 1.54 (1.47–1.61)* | ||
| 69 or older | 1.33 (1.27–1.38)* | ||
| Stage at diagnosis | |||
| I | Referent | ||
| II | 2.06 (1.93–2.21)* | ||
| III | 2.14 (2.04–2.26)* | ||
| IV | 0.31 (0.29–0.33)* | ||
| Histology | |||
| Endometroid carcinomas | Referent | ||
| Other carcinomas | 0.56 (0.54–0.58)* | ||
| Grade | |||
| 1, well differentiated | Referent | ||
| 2, moderately differentiated | 2.58 (2.48–2.68)* | ||
| 3, poorly differentiated | 3.45 (3.28–3.64)* | ||
| 4, undifferentiated; anaplastic | 3.25 (3.00–3.53)* | ||
| Unknown | 1.48 (1.42–1.54)* | ||
| Year of diagnosis | 0.99 (0.98–0.99)* | ||
SES, socioeconomic status.
Model 1 includes only race and ethnicity, model 2 includes only neighborhood SES, and model 3 includes race and ethnicity, neighborhood SES, and all demographic and clinical covariates (age at diagnosis, stage at diagnosis, histology, grade, and year of diagnosis).
P<.001.
P< .05.