Table 8.
Comparison of genotype and allele distribution of IL-10 rs1800872 polymorphism in the present study with international and Indian studies
| Studies | Country (Ethnicity) | Cases | Controls | P | ||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Genotypes (%) | Genotypes (%) | |||||||
|
|
|
|||||||
| CC | CA | AA | CC | CA | AA | |||
| Present study | Indian (South Asian) | 104(52.2) | 73(36.6) | 22(11.05) | 96(44.6) | 94(43.72) | 25(11.63) | 0.07 |
| Alkhurji et al.[55] | Saudi Arabia (Asia) | 28(43.1) | 28(43.1) | 9(13.8) | 32(49.2) | 23(35.4) | 10(15.4) | 0.53 |
| Bahadori et al.[72] | Iran (Asian) | 8(9.4) | 34(40) | 43(50.6) | 22(21.2) | 49(47.1) | 33(31.7) | 0.01* |
| Bohiltea and Radoi,[68] | Romania (Caucasian) | 30(69) | 33(69) | 6(69) | 35(64) | 26(64) | 3(64) | 0.36 |
| Cochery-Nouvellon et al.[73] | Italy (Caucasian) | 24(40) | 34(56.7) | 2(3.3) | 65(57.0) | 37(32.5) | 12(10.5) | 0.005* |
| Maskhina et al.[74] | Russia | 123(43.31) | 136(47.89) | 25(8.80) | 155(54.58) | 116(40.85) | 13(4.58) | 0.01* |
| Liu et al.[50] | China (East Asian) | 91(45.5) | 79(39.5) | 30(15.0) | 148(49.3) | 116(38.6) | 36(12.0) | 0.5 |
| Parveen et al.[57] | Indian (South Asian) | 73(57) | 41(32) | 14(11) | 77(11) | 66(41) | 18(11) | 0.25 |
| Zammiti et al.[60] | Tunisia (African) | 206(58.9) | 93(26.6) | 51(14.1) | 134(67) | 41(20.5) | 25(12.5) | 0.15 |
*P<0.05 considered significant