Table 2.
Endogenous Steroid Hormone Levels for Endometriosis Case Subjects and Matched Control Subjects in Nurses’ Health Study II, 1996–2009a
| Hormone | Cases (n = 446) | Controls (n = 878) | ||
|---|---|---|---|---|
| Median | 10th–90th Percentile Range | Median | 10th–90th Percentile Range | |
| Estradiol, pg/mL | ||||
| Follicular | 40.7 | 22.5–81.5 | 40.4 | 18.2–88.8 |
| Luteal | 131.7 | 80.5–229.5 | 133.5 | 70.4–247.2 |
| Free estradiol, pg/mL | ||||
| Follicular | 0.50 | 0.27–0.89 | 0.49 | 0.24–1.02 |
| Luteal | 1.57 | 0.91–2.74 | 1.63 | 0.90–2.87 |
| Estrone, pg/mL | ||||
| Follicular | 39.8 | 24.8–64.4 | 38.1 | 23.9–65.5 |
| Luteal | 88.4 | 51.6–152.2 | 84.8 | 50.5–155.0 |
| Testosterone, ng/dL | 24.1 | 14.5–40.4 | 24.9 | 15.4–38.6 |
| Free testosterone, ng/dL | 0.19 | 0.09–0.34 | 0.19 | 0.10–0.36 |
| Progesterone, ng/mL | 13.1 | 2.25–22.9 | 13.5 | 1.38–26.2 |
| SHBG, nmol/L | 68.7 | 32.8–125.2 | 68.5 | 33.4–126.0 |
Abbreviation: SHBG, sex hormone binding globulin.
a Some participants were missing information on follicular estradiol (99 cases, 215 controls), luteal estradiol (69 cases, 137 controls), follicular free estradiol (102 cases, 222 controls), luteal free estradiol (69 cases, 138 controls), follicular estrone (99 cases, 211 controls), luteal estrone (68 cases, 137 controls), testosterone (5 cases, 11 controls), free testosterone (21 cases, 45 controls), progesterone (64 cases, 45 controls), or SHBG (19 cases, 126 controls).