FIG. 2.
Effect of FSS in blood vessel structure and function. (a) 70 kDa red-fluorescent dextran permeability assay. Vessels generated under flow show high endothelial integrity and reduced permeability compared to vessels under static condition. (b) Reduced monocyte extravasation in vessels formed under flow. Monocytes are indicated with white arrows. Endothelial vessels are stained for F-actin(red), VE-cadherin (green), and DAPI (blue). Adapted with permission from Pérez-Rodríguez et al., J. Biomicrofluidics 15, 0541012 (2021). Copyright 2021 Authors, licensed under a Creative Common Attribution (CC BY) license.67