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. 2023 Aug 5;25(3):29. doi: 10.1007/s10544-023-00671-1

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© The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 2 — Summarized hydrodynamic diameter and PDI for all liposomal configurations. Average diameter and PdI values were calculated for each unique formulation and separated by (A) empty liposomes and (B) curcumin-loaded liposomes. Solid points represent monodisperse formulations (PdI ≤ 0.220) and translucent points represent polydisperse formulations (PdI > 0.220). Each column fixes a unique parameter as the independent variable (e.g. flow rate, lipid concentration, or aqueous:organic ratio), and for each column the different colors indicate unique formulations (i.e. unique combinations of the other two non-independent variable factors). Asterisk and error bars represent mean values ± standard deviation. For diameter averages, only monodisperse formulations were considered while for PdI averages all measurements were considered