Table 4.
Side effects assessed with FACT-ES questionnaire.
| Side effect | Patients with side effect on baseline (n) | Patients in which side effect improved (n) | % improved (from total patient group n = 26) | % improved (from patients with side effect) |
|---|---|---|---|---|
| Hot flashes | 26 | 15 | 58% | 58% |
| Joint pain | 25 | 16 | 62% | 64% |
| Insomnia | 25 | 15 | 58% | 60% |
| Cold sweats | 24 | 15 | 58% | 63% |
| Night sweats | 23 | 15 | 58% | 65% |
| Mood swings | 21 | 10 | 38% | 48% |
| Irritable feeling | 21 | 10 | 38% | 48% |
| Vaginal discharge | 19 | 7 | 27% | 37% |
| Vaginal dryness | 19 | 8 | 31% | 42% |
| Lost interest in sexa | 18 | 5 | 19% | 28% |
| Weight gain | 18 | 7 | 27% | 39% |
| Bloated feeling | 18 | 13 | 50% | 72% |
| Headache | 17 | 8 | 31% | 47% |
| Lightheaded/dizziness | 16 | 9 | 35% | 56% |
| Pain/discomfort with intercoursea | 15 | 6 | 23% | 40% |
| Breast sensitivity/tendernessa | 13 | 9 | 34% | 69% |
| Vaginal itching/irritationa | 9 | 4 | 15% | 44% |
| Diarrhea | 6 | 4 | 15% | 67% |
| Vomiting | 3 | 3 | 12% | 100% |
| Vaginal bleeding or spotting | 2 | 1 | 4% | 50% |
aFor this item some patients were missing, vaginal itching n = 1, pain/discomfort with intercourse n = 5, lost interest in sex n = 1, breast sensitivity/tenderness n = 2.