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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Laryngoscope. 2023 Feb 6;133(9):2066–2072. doi: 10.1002/lary.30601

Table 3.

Demographics and tumor characteristics of included studies in the systematic review and meta-analysis.

Authors Feng et al. Tran et al. Armstrong et al.
Total patients 149 387 361
Patients taking metformin (%) 42 (28) 46 (12) 19 (5)
Mean age (years) 69.6 60.6 ND
Male (%) 80 (54) 180 (47) ND
Caucasian (%) 81 (54) ND ND
Mean length of observation (months) 30.6 30.8 ND
Mean initial tumor size (mm) 8 11.9 ND
Tumor growth (%) 65 (44) 216 (56) 319 (88)