Table 2:
Serum lipids, renal function tests and inflammatory markers of the studied population
Characteristics | T2DP (n = 197) | Controls (n = 197) | *P-value | ||
---|---|---|---|---|---|
| |||||
X ± SD | 95% CI | X ± SD | 95% CI | ||
Serum lipids | |||||
Triglycerides (mmol/L) | 1.81 ± 0.58 | 1.52 – 2.03 | 0.78 ± 0.31 | 0.69–0.82 | 0.008 |
Total cholesterol (mmol/L) | 3.36 ± 0.27 | 3.07 – 3.62 | 3.34 ± 0.19 | 3.27 – 3.46 | 0.972 |
LDL-Cholesterol (mmol/L) | 2.02 ± 0.41 | 1.74 – 2.36 | 1.53 ± 0.32 | 1.41 – 1.66 | 0.011 |
HDL-Cholesterol (mmol/L) | 0.29 ± 0.08 | 0.22 – 0.35 | 0.65 ± 0.12 | 0.59 – 0.73 | 0.009 |
Renal function tests | |||||
Urea (mmol/L) | 8.11 ± 2.42 | 7.05 – 8.89 | 4.91 ± 0.37 | 4.70 – 5.05 | 0.013 |
Uric acid (µmol/L) | 351.6 ± 62.07 | 312.57 – 390.84 | 219.8 ± 34.63 | 204.09–237.02 | 0.015 |
Creatinine (µmol/L) | 139.01 ± 27.53 | 113.28 – 173.92 | 74.11 ± 13.17 | 70.21 – 77.5 | 0.007 |
GFR (ml/min) | 58.00 ± 12.57 | 41.55 – 76.01 | 107.39 ± 37.61 | 94.67 – 115.58 | 0.006 |
Albumin (g/L) | 30.94 ± 5.13 | 23.62 – 41.05 | 59.17 ± 4.83 | 58.03 – 66.01 | 0.018 |
Inflammatory markers | |||||
Fibrinogen (g/L) | 1.67 ± 0.34 | 1.60 – 1.87 | 1.23 ± 0.19 | 1.12 – 1.4 | 0.023 |
CRP (g/L) | 1.42 ± 0.27 | 1.29 – 1.94 | 0.87 ± 0.12 | 0.8 – 0.97 | 0.019 |
P-value: significant difference between type 2 diabetic patients and controls using independent sample Student’s t-test; T2DP: type 2 diabetic patients; X: average; SD: standard deviation; CI: confidence interval, GFR: Glomerular filtration rate; CRP: C protein reactive