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. 2023 Jul 25;25(7):470–482. doi: 10.22074/CELLJ.2023.1982707.1188

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Fig.6 — Cell cycle progression assay of -ERMP1 CRC cells using flow cytometry analysis. A-C. Results showed that the distribution of cells in S phase significantly decreased by knock-down of ERMP1 under normal condition or serum free and DTT exposure as compared with each scramble controls. D, E. However, following 5-FU and cisplatin treatment, the number of cells in S phase expanded compared with their scramble cells. F. Via ERMP1 overexpression, cell distribution in G1 has remarkably reduced without an obvious rise in S phase. Values are defined as the mean ± SD. **; P<0.01, ***; P<0.001, ****; P<0.0001 vs. each scramble control. Two-way ANOVA multiple comparison was used, SF; Serum free, DTT; Dithiothreitol, and CIS; Cisplatin.